简单来说，FDA对这类产品保有热情，肯定了“其为实现持久、无需用药的缓解带来的潜力“；同时，也对其“不可预测的长期毒性”保持警惕，承诺将“逐案合作”、“审慎引导”临床开发。
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This little oversight can be exploited: Say mario wants to collect a star to finish a level. He needs to position himself somewhat close to the star, but only his position after modulo 65536 is used for collision detection. We can use another exploit to make Mario gain massive velocity and the physics engine will allow him to clip through walls with it. However, with great velocity comes the price of leaving the map (going out of bounds). Therefor, we use the module operation to still force a collision detection with the star.